Characterization of the Interaction between CD45 and CD45-AP
نویسندگان
چکیده
منابع مشابه
CD45-associated protein inhibits CD45 dimerization and upregulates its protein tyrosine phosphatase activity Running head: CD45-AP INHIBITS CD45 DIMERIZATION
CD45, a receptor-like protein tyrosine phosphatase (PTP), plays an essential role in lymphocyte development and immune responses. Recent evidence suggests that dimerization of CD45 downregulates its function. However, the mechanisms by which CD45 dimerization is regulated remain unclear and there is no direct evidence that the PTP activity of CD45 dimers is less than that of monomers. CD45 in l...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1995
ISSN: 0021-9258
DOI: 10.1074/jbc.270.36.21151